NEUROPATHOLOGY

GENERAL OBJECTIVES: Neuropathology concerns itself with diseases of the central and peripheral nervous systems and skeletal muscle, and their manifestations in other body systems. In the course of training, residents must acquire competence in the pathological diagnosis of neurological disease, using as appropriate, electron microscopy, fluorescence microscopy, histochemistry, and other special methods relevant to the study of the nervous system. A sound basis in anatomical pathology, and in the anatomy, physiology, and biochemistry of the nervous system is essential to the interpretation of the neurological disease. Residents must be competent to correlate neuropathological findings with clinical features and the results of special investigations, and be able to advise clinical colleagues on the choice of investigative procedures and their interpretation. Residents must also acquire skills that will permit them to undertake laboratory management, supervision of neuropathology technical laboratories, and postgraduate continuing education.

The purpose of the required training is to give the resident a degree of independent responsibility for clinical decisions; an opportunity for further development of the skills required in making effective relationships with patients; the consolidation of competence in primary clinical and technical skills across a broad range of medical practice; and an understanding of the nature of the relationships between a referring physician and the consulting neuropathologist.

The training requirements that follow are a minimum. Residents, especially those contemplating an academic career, are encouraged to take additional training particularly in research.

INTRODUCTION:A university wishing to have a program in neuropathology accredited must also sponsor an accredited program in anatomical pathology or general pathology.

The purpose of this document is to provide program directors and surveyors with an interpretation of the general standards of accreditation as they relate to the accreditation of programs in neuropathology.

CONTENT AND ORGANIZATION OF THE RESIDENCY PROGRAM

There must be an organized program of rotations and other educational experiences, both mandatory and elective, designed to provide each resident with the opportunity to fulfill the educational requirements and achieve competence in the specialty.

The content and organization of each accredited program in neuropathology must be consistent with the specialty training requirements.

Liaison arrangements within the faculty should ensure that clinical training during the basic clinical year, in fulfilment of the specialty training requirements, meets the needs of residents in neuropathology.

Residents must be provided with increasing individual professional responsibility, under appropriate supervision, according to their level of training, ability, and experience for all aspects of the preparation, interpretation, and reporting of neuropathological material.

RESOURCES:There must be sufficient resources including teaching faculty, the number and variety of patients, physical and technical resources, as well as the supporting facilities and services necessary to provide the opportunity for all residents in the program to achieve the educational objectives and receive full training as defined by the specialty training requirements in neuropathology.

In those cases where a university has sufficient resources to provide most of the training in neuropathology but lacks one or more essential elements, the program may still be accredited provided that formal arrangements have been made to send residents to another accredited residency program for periods of appropriate prescribed training.

Learning environments must include experiences that facilitate the acquisition of knowledge, skills, and attitudes relating to aspects of age, gender, culture, and ethnicity appropriate to neuropathology.

  1. Teaching Faculty

There must be a sufficient number of qualified teaching staff to supervise residents and provide teaching in the basic and clinical neurosciences. The teaching staff should have an appropriate nucleus of full-time teachers.

  1. Volume and Variety of Pathological Material

Laboratory training must be based on adequate resources to ensure full training for each resident in all areas of neuropathology. The description of the integrated program should specify how the responsibility for each of the components of the program is shared by the participating institutions. The resources of the program, including volume and variety of pathological material, laboratory space and equipment, and medical, scientific, and technical staff, must be satisfactory to the Specialty Committee in relation to each of the following components:

    1. Autopsy Pathology

There must be adequate numbers of autopsies available to provide full training in gross autopsy techniques, histotechniques, and postmortem bacteriology techniques. The volume and diversity of material available for teaching must be satisfactory to the Specialty Committee. Instruction in postmortem prosection must be provided under the direction of staff pathologists, with particular reference to the handling of the brain and spinal cord.

    1. Surgical Neuropathology

There must be an adequate volume and range of surgically excised tissues to provide training in gross examination, dissection, and selection of appropriate blocks for histological study. Facilities must be available for quick frozen sections, preferably located close to the surgical theatres. The range of material must include central and peripheral nervous system tumours, muscle biopsies, and nerve biopsies.

    1. Neurocytology

There should be adequate material and facilities available for training in exfoliative neurocytology.

    1. Forensic Neuropathology

Residents must obtain experience in the special procedures which may be associated with medicolegal neuro-autopsies, including neonatal autopsies.

    1. Special Neuropathological Material

An opportunity should be provided to study neuropathological specimens from institutions for retarded children, psychiatric hospitals, and chronic hospitals.

    1. Pediatric Neuropathology

Facilities for training in the neuropathology of infants and children must be available to the program, with adequate volume and variety of pathological material.

    1. Special Methods

In addition to adequate facilities and equipment for routine fixation and staining of tissues, there must be adequate opportunity to develop skills associated with special staining procedures. Competence in the operation of the light microscope must be assured, including the applications of polarizing optics and fluorescent microscopy. The methods of tissue fixation for electron microscopy, and the operation of the instrument, must be thoroughly understood. There must also be adequate facilities and instruction in histochemistry, immunoperoxidase techniques, molecular biology and other special methods relevant to neuropathology.

  1. Clinical Services Specific to Neuropathology
    1. In-Patient

A clinical learning experience, in one or more of neurology, neurosurgery or psychiatry, is recommended and should be electively available to the resident.

    1. Laboratory

Instruction in laboratory management and quality assurance/improvement is essential.

    1. Consultation

An active consultation service is essential to provide experience in acting as a consultant to clinical colleagues. Residents should participate in consultations, both elective and emergency, on a continuing basis during training.

The residency program must provide opportunity for residents to acquire the skills and attitudes appropriate to the provision of neuropathological diagnostic and consultative services, and to function effectively as members of a team of laboratory physicians in such a setting. Residents must acquire competence in the pathological diagnosis of disease in the central and peripheral nervous system and skeletal muscle, and must be able to correlate systemic findings with neuropathological abnormalities.

Residents must be competent to advise colleagues regarding the choice of investigative procedures and their interpretation.

  1. Supporting Services — Clinical, Diagnostic, Technical
    1. Liaison with Other Specialties and Subspecialties

There must be appropriate liaison and appropriate exposure to teaching services in neurology, neurosurgery and psychiatry. This may include clinico-pathological conferences, attendance at rounds of clinical services, and interdisciplinary clinics. Liaison within the faculty must be such as to ensure that any clinical training taken on these services meets the needs of residents in neuropathology.

There must be appropriate liaison with teaching services in anatomical pathology. Residents must be competent in the broad field of anatomical pathology, and must work in close association with an accredited residency program in anatomical pathology. There must be effective interaction between neuropathology residents and residents in anatomical and general pathology in the study of autopsy cases.

    1. Oncology

There must be close association with an active teaching service in oncology in order that a full range of neoplastic pathology may be available for teaching. The pathological changes induced by radiotherapy, chemotherapy and immunotherapy must be clearly understood by residents.

    1. Diagnostic Imaging

There must be an active service in diagnostic neuroradiology with arrangements for the instruction of residents in all relevant forms of diagnostic imaging. There should be provision for the study of clinico-pathological correlations with relevant radiologic findings.

ACADEMIC AND SCHOLARLY ASPECTS OF THE PROGRAM:

The academic and scholarly aspects of the program must be commensurate with the concept of a university postgraduate education. The quality of scholarship in the program will in part, be demonstrated by a spirit of enquiry during clinical discussions, rounds, and conferences. Scholarship implies an in-depth understanding of basic mechanisms of normal and abnormal states and the application of current knowledge to practice.

  1. Organized Scholarly Activities

The program must include lectures and seminars, which may be interdisciplinary in nature, special courses, technical demonstrations, and journal clubs. The teaching program should lay emphasis on etiology, pathogenesis, and tissue reactions. Regular conferences between the neuropathology service and the clinical services for discussion of clinical cases are essential.

  1. Basic and Clinical Sciences Relevant to Neuropathology

The program must include organized teaching in the basic sciences and advanced scientific knowledge related to pathology, including anatomy, histochemistry, metabolism, immunology, molecular biology, genetics, and photography including microphotography.

  1. Biomedical Ethics

The academic program must ensure that residents gain an understanding of the basic principles and practice of biomedical ethics as it relates to neuropathology.

  1. Communication Skills

The program must ensure that residents learn effective communication skills for interacting with patients and their families, colleagues, co-workers from other disciplines, and students. Clearly defined educational objectives for teaching these skills should be in place.

  1. Patient Care Team

Residents must be given opportunities to develop effective skills in collaborating with all members of the patient care team.

  1. Teaching Skills

Residents must be given opportunities to develop effective teaching skills by teaching junior colleagues and students, as well as through conference presentations, clinical and scientific reports, and patient education.

  1. Management Skills

Residents must be given opportunities to develop skills in management as applied to neuropathology such as efficient practice and records management and the ethical use of health care resources. Residents should also be prepared for their role as a health care advocate.

  1. Quality Assurance/Improvement

The program must provide residents with opportunities to gain an understanding of the principles and practice of quality assurance/improvement. Opportunities should be provided for residents to participate actively in such programs in their hospital departments.

  1. Research Opportunities for Residents

There must be a faculty member with the responsibility to facilitate the involvement of residents in research and other scholarly work. The academic program must provide the opportunity for residents to learn biostatistics and the critical appraisal of research methodology and medical literature. Such teaching must include issues related to age, gender, culture, and ethnicity in research protocols and data presentation and discussion. It is desirable that residents have the opportunity to participate actively in research programs. An active research program in one or more of the institutions involved in the residency program is considered essential, and all residents should be given the opportunity to follow the progress of such research programs.

  1. Faculty Research

A satisfactory level of research and scholarly activity must be maintained among the faculty identified with the program.

  1. Life-Long Learning

All programs must promote development of skills in self-assessment and self-directed life-long learning. To promote this end, the program should provide opportunities for residents to attend conferences outside their own university.

SPECIALTY REQUIREMENTS:

Approved training include:

  1. Basic clinical training.
  2. Approved residency in neuropathology
  3. Approved residency in anatomical pathology, with experience in both autopsy and surgical work

PROGRAMS (WITH TRAINING REQUIREMENTS):

Diplomas(Dip):

Six months of approved residency training.

Doctor of Medicine(M.D):

Eighteen months of approved residency training.

Doctor of Philosophy(Ph.D):

Forty eight months(four years)of approved residency training.